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Rare Medication

Medicine profile

Teprotumumab

teprotumumab

Teprotumumab (Tepezza): An IGF-1R inhibiting monoclonal antibody for thyroid eye disease, given as a course of intravenous infusions. Procurement-oriented reference for licensed buyers - not medical advice, and availability depends on region and authorization.

Not listedFDA drug shortage database - checked 20 Sept 2026Shortage page

What this medicine is commonly used for

Procurement teams reference Teprotumumab when aligning formulary decisions, documenting a named patient request, or preparing a quotation for a destination country where the product is not routinely stocked.

Informational only. Treatment decisions belong to qualified clinicians and to local labeling.

Shortage and sourcing context

Demand is concentrated in a small number of specialist centres, and the course structure means orders are planned per patient rather than held as stock. Registration outside its original market is limited, so cross-border requests dominate.

How it is presented

Examples of presentations referenced for this medicine. Actual market presentations vary by country and registration, so check the pack in front of you.

  • Powder for concentrate for solution for infusion

Who typically asks us about this medicine

  • Patients and families who cannot fill a prescription locally
  • Hospital pharmacies managing formulary access during a shortage
  • Clinics with defined treatment pathways and continuity of care
  • Procurement teams coordinating licensed cross-border sourcing
Full reference text(expand)

Teprotumumab (Tepezza): An IGF-1R inhibiting monoclonal antibody for thyroid eye disease, given as a course of intravenous infusions. Procurement-oriented reference for licensed buyers - not medical advice, and availability depends on region and authorization.

Procurement context

Procurement teams reference Teprotumumab when aligning formulary decisions, documenting a named patient request, or preparing a quotation for a destination country where the product is not routinely stocked.

What makes it hard to source

Demand is concentrated in a small number of specialist centres, and the course structure means orders are planned per patient rather than held as stock. Registration outside its original market is limited, so cross-border requests dominate.